49ers fear QB Garoppolo sustained season-ending ACL injury

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Garoppolo will have an MRI on Monday to determine the severity of the injury. The creative play calling of head coach Kyle Shanahan will lead to plenty of open plays for the running backs, which will keep the team in the game against a unsafe and explosive Chiefs offense. "We'll find out tomorrow".

With his 49ers in pursuit of a fourth-quarter comeback and driving into scoring range, Garoppolo attempted a rush towards the sidelines when it appeared that his left knee gave out before contact with the Chiefs' Steven Nelson. "We said one day we were going to take over the Chiefs Kingdom".

San Francisco proceeded to kick it deep rather than try an onside kick.

"Any time you lose your starting quarterback, that's a big deal". "He told me to lead these guys".

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"I told him I would be praying for him and that I love him", Beathard said (via the Chronicle ). "I haven't had a chance to see him yet, but I feel for him". Disappointing I know, but still a solid National Football League record-breaking pace.

The 49ers also lost star cornerback Richard Sherman to a calf injury, the third defensive back to get banged up in the game.

Beathard will make his first start of the season next Sunday when the 49ers travel to Carson to face the Los Angeles Chargers. Strong safety Jaquiski Tartt was inactive with a shoulder injury and free safety Adrian Colbert hurt his ankle, forcing a bunch of backups to play significant snaps. He connected Sunday on 20 of 30 throws for 251 yards with two touchdowns and no picks while the 49ers outgained the Chiefs in yardage 406-384 despite the early 28-point deficit. The 49ers fell 38-27 to Kansas City, dropping their record to 1-2. And after Garoppolo's TD toss to Marquis Goodwin in the third quarter made it 35-24, there was a sense of optimism on the San Francisco sideline.

Exactly how this impacts the remainder of San Francisco's season is yet to be determined, although it can't look good. "He started for us a few games last year and did his thing, helped get our first win of the season last year against the Giants".