England striker Kane was expected to be sidelined for at least another fortnight after damaging ankle ligaments at Bournemouth on March 11. The injury forced the striker out of the England friendlies against the Netherlands and Italy.
While there was no guarantee that the Chelsea league fixture will see Kane return, Pochettino revealed that it is an eventuality and may happen next week if not this one.
Progress is going well for Kane, who should be fit and ready for this Summer's World Cup in Russian Federation. Arsenal and Chelsea always are tough games, because they are derbies and, for me, it is a similar type of opponent.
Both players were involved in global duty this week, and will be checked on before the crucial matchup. When you play this type of game, the pressure is for both teams.
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'I can not say no, but I can not say yes. This is not a decisive game, but always it is important for your confidence, your motivation. "We are focused on performance and the possibility to be better than them and we have the capacity to win the game", Pochettino added.
"We need to assess him over the next few days".
Pochettino, who ranks Spurs' rivalry with Chelsea on a par with Arsenal, does not think it is a winner-takes-all game. "Every day he is improving", Pochettino said.
"It is always a massive game because it is a London derby". He is very positive and he is doing very well. We are doing fantastic and we are so happy. "I wasn't there. Only I can talk for myself, how he is at Tottenham, and we try to help him to achieve what he wants". Tottenham manager Mauricio Pochettino says "I can not say no, but I can not say yes" about Kane's availability for the match at Stamford Bridge. "That is not what counts".