Now, before you panic, there's no suggestion yet that occasionally relying on an ibuprofen will make your balls shrivel up and die. Unfortunately, a new study says that ibuprofen can actually reduce fertility rates in men.
The Danish research team warned: "Ibuprofen appears to be the preferred pharmaceutical analgesic for long-term chronic pain and arthritis". Essentially testosterone levels were normal but the men in the ibuprofen group had higher amounts of luteinizing hormone, which stimulates testosterone production.
It has already been linked with fertility problems in women taking the drug.
The human brain compensates for testosterone deficiency by producing luteinizing hormone (LH), which sends a signal to the testicles to produce more testosterone.
The research focused on men given 600mg of ibuprofen twice a day, which isn't the norm for the average bloke.
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Advil and Motrin are two brand names for ibuprofen, which can be bought over-the-counter as a pain reliever, and is typically used by athletes.
Professor Allan Pacey from the University of Sheffield, cautions: "The results suggest that long-term use (several weeks) of ibuprofen can affect the production of the male hormone by the testicles". Some took 1,200 milligrams of ibuprofen daily, which is the maximum limit as directed, over a six-week period.
Fortunately, the condition went away in the volunteers when they stopped taking the medication. The resulting imbalance produced a condition called compensated hypogonadism, which is associated with lower fertility, depression and an increased risk for cardiovascular events like strokes or heart failures.
"The safety and efficacy of active ingredients in these products has been well documented and supported by decades of scientific study and real-world use", said Mike Tringale, a spokesman for the association, according to Fox News.
To avoid these side-effects, doctors caution against taking Ibuprofen for more longer than ten days in a row, per the FDA's warning.
At the end of the study, the men who took ibuprofen had developed compensated hypogonadism, a condition usually associated with smokers, elderly men and those with reproductive issues or physical disorders.